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pentobarbital will decrease the extent or result of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will reduce the level or result of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Sturdy or moderate CYP3A4 inducers could enhance amount of diazepam